Dr. Kasia Roberts

Dr. Kasia Roberts is a Professor of Chemistry in the Department of Math and Physical Sciences at Rogers State University.

Education

Ph.D. Chemistry
Thesis: Products of activation and DNA adduct formation of the antitumor drug Nitracrine
M.S. Biotechnology
Thesis: The relevance of enzymatic oxidation to antitumor potency of imidazoacridinone derivatives

University of Science and Technology, Gdansk, Poland

Professional Experience

2020-Present, Professor
2014-2020, Associate Professor
2008-2014, Assistant Professor
Department of Math and Physical Sciences, Rogers State University, Claremore, OK

2003-2008, Adjunct Professor
Chemistry Department, Tulsa Community College, Tulsa, OK

2000-2002, Postdoctoral Fellowship
National Center for Toxicological Research, Food and Drug Administration

1995-1999, Teaching Assistant, Department of Chemistry
University of Science and Technology, Gdansk, Poland

Professional Affiliations

• American Chemical Society

Research Training

• Ames Laboratory, Iowa State University, Ames, IA, April-June 1999.
• National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR, April-June 1998 and March 2000-July 2002 (postdoctoral appointment).
• University of Tulsa – Analysis of Bio-trap ¹³C gasoline additives concentrations and biodegradability. January-September 2008.
• Consulting research for Microbial Insights company on gasoline additives, such as Methyl-t-butyl ether (MTBE), t-Butyl alcohol (TBA), Benzene, Chlorobenzene, Xylene, Naphtalene, 1,4-Dioxane. September 2008-September 2010.

Research

• Metabolism and mechanism of action of DNA-reacting compounds (nitroacridinone, heterocyclic and aromatic amines), heterocyclic and aromatic amine DNA adducts syntheses, identification of DNA adducts from epithelial cells of human breast, polymorphism of carcinogen activating enzymes in relevance to breast carcinogenesis
• Bioremediation of hydrocarbons in soil and gasoline additives in water reservoirs
• Physical exercise and stress markers
• Heavy metals in soil, water and food samples

Grants

• Principal investigator of a research grant “Metabolism of nitroaromatic compounds of antitumor potency.”University of Science and Technology, Gdansk, Poland (1999)
• Principal investigator of the Oklahoma Idea Network of Biomedical Research Excellence grant, 2012 “Effect of exercise on the level of salivary endocrinological stress markers”
• Equipment grants (Vernier software and technology equipment, Microplate reader, Gas chromatography instrument): OK- INBRE 2011, INBRE 2014

Publications and Presentations

Ph.D Thesis: “Products of activation and DNA adduct formation of the antitumor drug Nitracrine”, Gdansk University of Science and Technology, Gdansk, Poland 1994

M.Sc. Thesis: “The relevance of enzymatic oxidation to antitumor potency of imidazoacridinone derivatives”, Gdansk University of Science and Technology, Gdansk, Poland 2000

“The effects of physical exercise on the levels of salivary stress markers”58^th Annual Pentasectional Meeting of American Chemical Society, Tulsa, March 2013

Oklahoma Research Day at the Capitol, “The effects of physical exercise on the levels of salivary stress markers”, Oklahoma City, March 2012

Ambrosone Christine, Abrams Sara, Gorlewska-Roberts Katarzyna, and Kadlubar Fred, Hair Dye Use, Meat Intake, and Tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells, Archives of Biochemistry and Biophysics, 464, 169-175, 2007

Gorlewska-Roberts Katarzyna, Teitel Candee, Lay Jackson, Roberts Dean, and Kadlubar Fred, Lactoperoxidase-catalyzed activation of carcinogenic aromatic and heterocyclic amines, Chemical Research in Toxicology, 17, 1659-1666, 2004

Gorlewska-Roberts Katarzyna, Wiese Frederick W., and Kadlubar Fred F. Recent advances in our understanding of the role of peroxidases in human carcinogenesis, Molecular and Therapeutic Aspects of Redox Biochemistry, OICA International UK, 2003

Gorlewska-Roberts Katarzyna, Green Bridgette, Fares Manal, Ambrosone Christine, and Kadlubar Fred. Carcinogen-DNA adducts in human breast epithelial cells Environmental and Molecular Mutagenesis, 39, 184-192, 2002

Gorlewska Katarzyna, Mazerska Zofia, Sowinski Pawel, Konopa Jerzy. Products of activation of the antitumor drug Ledakrin (Nitracrine) in vitro. Chemical Research in Toxicology, 14, (1), 1-10, 2001

Gorlewska Katarzyna, Teitel Candee, Kadlubar Fred F. The role of lactoperoxidase-catalyzed activation of aromatic and heterocyclic amines in breast cancer. American Association for Cancer Research Annual Meeting, New Orleans, March 2001, abstarct no. 4800

Gorlewska Katarzyna, King Roberta, Mazerska Zofia, Konopa Jerzy, Kadlubar Fred. Metabolic activation and DNA-adduct formation by the anticancer drug Nitracrine. American Association for Cancer Research Annual Meeting, Philadelphia, April 1999, abstract no. 31

Mazerska Zofia, Gorlewska Katarzyna, Kraciuk Agnieszka, Konopa Jerzy. The relevance of enzymatic oxidation by horseradish peroxidase to antitumor potency of imidazoacridinone derivatives. Chemico.-Biological Interactions, 115, 1-22, 1998

Gorlewska Katarzyna and Konopa Jerzy, International workshop on drug metabolism, Copenhagen, Denmark, June 1998, abstract no. 46

Gorlewska Katarzyna, Mazerska Zofia, Konopa Jerzy. Metabolic activation pathway of antitumor drug Ledakrin (Nitracrine). Studies with the use of model system. Experimental and Toxicol. Pathol., 48, suppl. II, 155-160, 1996

Gorlewska Katarzyna, Mazerska Zofia, Konopa Jerzy, Study on metabolic activation of antitumor active imidazoacridinone derivatives. 5^th International Symposium on Molecular Aspects of        Chemotherapy, Gdansk, August 1995, abstract no. 17